ABSTRACT
Background: The use of implantable cardiac devices in patients with sudden cardiac arrest has contributed to their survival. Aim: To determine the survival rate at 30 days and one year after hospital discharge of patients who had a cardiac arrest with subsequent placement of an implantable cardiac device. Material and Methods: Twenty-three patients older than 18 years who presented sudden extra-institutional or intra-institutional death with subsequent implantation of an implantable cardiac device and whose survival was recorded at 30 days and one year, were included. A univariate analysis was performed. Results: Eighteen patients had an extra institutional cardiac arrest. All patients were discharged alive. We could not ascertain the health status of one patient at follow-up. Twenty-one patients had a Cerebral Performance Category (CPC) of 1 at discharge. One patient died of a stroke within 30 days and one patient died due to an arrhythmic electrical storm one year later. Twenty patients survived at least one year after hospital discharge. Conclusions: Survival at 30 days and one year, was high in patients with sudden death or cardiac arrest who required intracardiac devices.
Subject(s)
Humans , Defibrillators, Implantable , Heart Arrest/therapy , Patient Discharge , Time Factors , Survival Rate , Death, Sudden, Cardiac/etiologyABSTRACT
Objetivo Desarrollar un instrumento destinado a evaluar las estrategias de afrontamiento ante la enfermedad crónica en población adolescente. Sujetos y método Con base a una revisión teórica y entrevistas semiestructuradas a adolescentes, se construye un cuestionario que es finalmente evaluado por jueces expertos en tanto comprensión, pertinencia y viabilidad. Resultados Se propone una escala compuesta por 60 reactivos agrupados en 12 familias de afrontamiento. Conclusión La escala puede ser una herramienta útil para un clínico al entregar información clave sobre la vivencia y las formas de afrontar la enfermedad en un adolescente.
Objective To develop a tool to evaluate coping strategies for chronic illness in adolescents. Subjects and method Based on a theoretical review and semi-structured interviews with adolescents, a questionnaire was prepared that was finally evaluated by judges experienced in in understanding, relevance and viability. Results A scale is proposed that consists of 60 items grouped into 12 coping families. Conclusion The scale may be a useful clinical tool to provide key information about the experience and ways to cope with illness in adolescents.
Subject(s)
Humans , Male , Female , Adolescent , Adaptation, Psychological , Chronic Disease/psychology , Surveys and QuestionnairesABSTRACT
Background:Overexpression/amplification of the HER2 gene in advanced gastric cancer is a predictor of response to adjuvant therapy with monoclonal antibodies.Aim: To determine the frequency of HER2 gene overexpression and amplificationin advanced gastric cancer. Material and Methods: One hundred nine advancedgastric cancer biopsy specimens, from 76 men and 33 women aged 67 ± 14 and 62± 12 years respectively, were selected. Three histological patterns (diffuse, intestinaland mixed) were recognized. Automated immunohistochemistry was performedwith monoclonal c-erbB-2 (NCL-356) Novocastra. Fluorescent in situ hybridization (FISH) for HER2 was performed in positive cases. Results: In 39% of cases,immunohistochemical staining was negative. It was 1+, 2+ and 3+ positive in 15,36 and 11% of cases, respectively. It was positive in 16% and 3% of intestinal typeand mixed carcinomas, respectively. It was negative in all diffuse carcinomas. FISHwas performed in 39 (2 +) cases and in 11 (3 +) cases. The gene amplification waspositive in two (2 +) and 11 (3 +) cases (11.9%). The overall concordance betweenimmunohistochemical staining and in situ hybridization was 85%. Conclusions: Inadvanced gastric cancer, HER2 gene overexpression or amplification was observed in11% and 12% of cases, respectively.
Subject(s)
Aged , Female , Humans , Male , Middle Aged , Adenocarcinoma/genetics , Gene Amplification/genetics , /genetics , Stomach Neoplasms/genetics , Adenocarcinoma/pathology , Gene Expression , In Situ Hybridization, Fluorescence , Stomach Neoplasms/pathology , Tissue Array AnalysisABSTRACT
El el Hospital Juan XXIII, respecto a la etiología más frecuente, la coxalgia, se constata que la más alta incidencia está en la artritis séptica de cadera, por lo general en lsa edades de 1 a 3 años, siendo los gérmenes más frecuentes el Stafilococo y el Streptococo